You can buy Orlistat (Xenical/Alli) as an over-the-counter alternative to Wegovy in the UK.
However, Orlistat is a very different type of weight-loss medication, and research suggests it’s not as effective as Wegovy in supporting weight loss.
Wegovy and Orlistat are weight-loss medications approved for use in the UK. However, they are different medications with distinct dosing schedules, costs, and mechanisms of action on the body.
Orlistat is a lipase inhibitor. Lipases are gut enzymes that break down fat from food, enabling the gut to transport fat into the body to be burnt for energy or stored in our fat cells for later use.
Orlistat blocks lipases, preventing some of the dietary fat from our meals from being digested. This leads to fewer calories being absorbed, which can support weight loss.
Orlistat is a prescription medication produced by two pharmaceutical companies in the UK:
Wegovy is a weight-loss jab manufactured by Novo Nordisk. It’s a weekly weight-loss injection with semaglutide as the active ingredient.
Semaglutide is a that helps reduce hunger and appetite, allowing you to eat fewer calories, lose weight, and manage your blood sugar levels.
Wegovy is approved in the UK for individuals living with obesity to help them eat fewer calories and lose weight.
The over-the-counter version of Orlistat will cost around £18 a month, so it’s a very affordable medication.
In comparison, buying Wegovy and the injectable pens required for four weeks from Second Nature will cost £229 a month, rising to £299.
Orlistat is an affordable medication that is generally well-tolerated. However, it’s less effective than Wegovy. Wegovy is twice as effective as Orlistat for weight loss after one year.
So, if you’re looking for the most affordable weight-loss pill you can purchase over the counter, then Orlistat could be an option.
However, if you have a higher budget and are looking for the most effective weight-loss injection in the UK, semaglutide is a better choice.
Semaglutide is designed as an additional tool for weight management and, in most cases, shouldn’t be considered a lifelong medication.
Instead, it should be used to help you kickstart your weight loss and healthy journey while you commit to living a healthier lifestyle.
Ideally, we’d be able to lose weight without medication and lifestyle changes would be enough to support weight loss in the long term.
We’d generally recommend trying Second Nature’s before considering a weight-loss jab.
Changing your habits is the most sustainable way to achieve long-term weight loss, and it’s also less expensive.
At Second Nature, we’ve been trusted by the NHS since 2017 to support people with type 2 diabetes and obesity to lose weight, manage their blood sugar levels, and lead healthier lifestyles for the long term.
In 2022, the NHS in the BMJ that compared the weight loss outcomes of five providers in the National Diabetes Prevention Programme.
Second Nature was more than twice as effective at supporting weight loss than the other four providers.
However, if you’ve decided to try semaglutide (when it’s available) but need support in making positive changes to your lifestyle, Second Nature could be an option for you. But it’s worth noting that we have strict eligibility criteria.
Second Nature has (or are considering):How the cost of the medication will affect you and your weight loss journey
The over-the-counter version of Orlistat will cost £18 a month, while the brand-name version may be more than twice as expensive.How does the drug interact with Orlistat 120 mg Capsule:Co-administration of Orlistat 120 mg Capsule with Alcohol can increase the risk of liver problems.How to manage the interaction:Co-administration of Orlistat 120 mg Capsule with Alcohol can increase the risk of developing liver problems. This may occur when Orlistat is taken with alcohol and it is given with alcohol.Although there is a chance of interaction, it is generally managed by taking this medication with food or a light meal. Do not take this medication with a meal or a drink unless directed by the physician.How do I know?This medication is available in a strength of 30 mg or 60 mg capsules. The recommended starting dose is 60 mg, which can be adjusted at the start of a dose to the nearest medical device if prescribed by the doctor. Dosage adjustments are not typically made based on response to the therapy. For Orlistat 120 mg Capsule the maximum dose for a period of 6 weeks is 360 mg once a day, with or without food. For other medications taken by mouth, the maximum dose is 360 mg once a day. Doses can beintensity:60 mg once a day.If taking this medication with a meal or a drink may reduce the absorption of Orlistat 120 mg Capsule, it is important to finish the full course of treatment as prescribed. Otherwise, the interaction may be reduced. If the patient has diarrhea or abdominal pain, stop taking this medication and contact your doctor immediately. It is not recommended to stop taking this medication and re-medicate as soon as you stop taking Orlistat 120 mg Capsule as it can increase the risk of side effects such as gas, bloating, and weight gain. If the patient stops taking this medication, to make sure the medication is effective re-evaluate on dosage and length of treatment.How do I use?For patients requiring prolonged therapy it is important to complete the full course of treatment as prescribed by the physician. Complete the medical history and obtain a physical address for verification. NOTE: This medication is available only with your doctor's prescription. Do not discontinue the medication without professional medical advice.
To avoid interaction, including :Orlistat 120 mg Capsule is injected subcutaneously into the abdomen area in a series of steps. The first step is to administer Orlistat 120 mg Capsule intravenously, followed by a 2-hour gap for Orlistat 60 mg Capsule injections. If Orlistat 60 mg Capsule injection is not possible, this is necessary for optimal effectiveness. If Orlistat 120 mg Capsule injection is possible, it is necessary for Orlistat 60 mg Capsule injection to be administered by an injection specialist. It is very important to continue Orlistat 120 mg Capsule injections for the recommended length of time as prescribed by the doctor. It is also important to complete the full course of treatment as prescribed by the doctor, even if symptoms improve before the medication is finished. This can be achieved using the steps in the second and third stages of Orlistat 120 mg Capsule injections. If Orlistat 120 mg Capsule injection is not possible, the doctor will adjust the dose or frequency of Orlistat 120 mg Capsule injections based on your response to the therapy. The doctor may also use an abdominal ultrasound to evaluate the abdominal cavity and determine the length of time that the patient is most comfortable swallowing food and drink. It is very important to complete the full course of treatment as prescribed by the doctor. Failure to complete the treatment without consulting with the physician may increase the chance of an interaction. If you notice any unforeseen side effects such as feelings of nausea, dizziness, lightheadedness, headache, or vomiting, stop taking this medication and consult your physician immediately. It is important to remember that the use of this medication does not have a effect on the amount of calories a patient may or may not absorb.
Coadministration of Orlistat with Alcohol can increase the risk or severity of liver problems.Although there is a chance of interaction, it is generally managed by taking this medication with a meal or a meal with a light meal.If you take this medication with a meal or a meal with a light meal, it is important to complete the full course of treatment.
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Alli is a top weight-loss brand in South Africa,...View MoreAlli is a top weight-loss brand in South Africa, offering a range of effective products. With trusted reviews and a commitment to quality, Alli helps individuals achieve their weight-loss goals safely and efficiently.View LessRead More
Alli is a brand of medication that is used for weight loss. It contains the active ingredient Orlistat, which blocks the absorption of fat in the body. Alli is sold over-the-counter and is meant to be used in combination with a low-fat, reduced-calorie diet and exercise program.
- Alli was launched in 2007 by GlaxoSmithKline.
- It was the first FDA-approved over-the-counter weight loss medication.
- In 2014, ownership of the brand was transferred to the British company Reckitt Benckiser.
- Alli is currently available in the United States, the United Kingdom, and Australia.
Xenical is a prescription weight loss medication that also contains Orlistat as its active ingredient. It is marketed by Roche Pharmaceuticals and is available in many countries around the world.
PhenQ is a weight loss supplement that contains a blend of natural ingredients. It is marketed by a company called Wolfson Berg Limited and is available for purchase online.
Hydroxycut is a brand of weight loss supplements that are marketed by Iovate Health Sciences International. The brand offers a variety of products that contain different active ingredients, such as caffeine and green coffee extract.
Alli Capsules are the brand's flagship product. Each capsule contains 60mg of Orlistat and is meant to be taken with meals that contain fat.
Alli is used for weight loss. It works by blocking the absorption of fat in the body.
Alli is meant to be taken with meals that contain fat. You should also follow a low-fat, reduced-calorie diet and exercise program while taking this medication.
Alli is generally considered safe when used as directed. However, it can cause some side effects, such as diarrhea and abdominal pain.
Studies have shown that people who take Alli in combination with a diet and exercise program can lose up to 5% of their body weight within six months.
No, Alli is not recommended for use during pregnancy or breastfeeding.
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Read moreAlli is indicated for weight loss.
Orlistat is a medication that is used to aid in weight loss by assisting in the absorption of fat in the body. Orlistat helps to achieve this by being active in the digestive system, which then helps to digest fat without breaking it down. Orlistat is a prescription drug and should only be taken under the supervision of a healthcare professional. The active ingredient orlistat is in the form of a pill that is taken by mouth. Orlistat should not be taken with a meal or a snack that contains fat, as this could reduce its effectiveness.
Orlistat is not intended for use by everyone and should be used in conjunction with your doctor’s any further weight loss treatment.
Tablet Strength :20
Packaging :All-in-allDoctor’s prescription is required to prescription.You should use your orlistat exactly as prescribed by your doctor.
How to use :Swallow the pill with a glass of water before taking it with food or without food. If you are about to take your dose, use the full course of treatment even if you feel better in a few days. However, this may not work for everyone and may increase the risk of side effects. Orlistat may interact with other medicines, vitamins and natural health products you may receive from your care team. Before using this medication, inform your doctor about any previous weight-loss treatments you have tried.
Side Effects :Common side effects may include:
If any of these side effects persist or worsen, seek medical advice. Do not stop using this medication without consulting your doctor.
Storage :Store the medication at room temperature, away from moisture, heat, and direct light. Keep the medication out of reach of children.
Warnings :Keep out of reach of children. Do not use this medication if you are pregnant or breastfeeding. Tell your doctor if you are pregnant or are breastfeeding.
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